CD46 抗体 (PE)
Quick Overview for CD46 抗体 (PE) (ABIN7673621)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE Anti-Human CD46 Antibody
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纯化方法
- 0
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纯度
- 0
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亚型
- IgG1, kappa
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应用备注
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- 4 °C
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储存方法
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- CD46
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别名
- CD46
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背景
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Synonyms: Complement membrane cofactor protein|measles virus receptor|MCP
Background: CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.
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分子量
- 0
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基因ID
- 4179
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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